1. Gene
  2. NIT1 - nitrilase 1 Gene

NIT1 - nitrilase 1 Gene

中文名称:腈水解酶 1

种属: Homo sapiens

基因 ID: 4817 | 基因类型: protein coding

关于 NIT1

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,118,105-161,125,445 (from NCBI)

This gene has 16 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 11.4), kidney (RPKM 10.4) and 25 other tissues.

功能概要

该基因编码与细菌和植物腈水解酶同源的腈水解酶蛋白家族成员,后者是将腈和有机酰胺裂解为相应的羧酸和氨的酶。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供,2010 年 6 月]

This gene encodes a member of the nitrilase protein family with homology to Bacterial and plant nitrilases, Enzymes that cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

NIT1 基因产物(4)

mRNA Protein Name
NM_001185092.2 NP_001172021.1 deaminated glutathione amidase isoform 2
NM_001185093.2 NP_001172022.1 deaminated glutathione amidase isoform 3
NM_001185094.2 NP_001172023.1 deaminated glutathione amidase isoform 4
NM_005600.3 NP_005591.1 deaminated glutathione amidase isoform 1

NIT1 蛋白结构

CN_hydrolase

CN_hydrolase: Carbon-nitrogen hydrolase (48 - 228)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
蛋白主名 其他名称

deaminated glutathione amidase

dGSH amidase

NIT1 抗体

目录号 产品名 应用 反应物种
HY-P81656 NIT1 Antibody (YA1401) WB, IP Human, Mouse, Rat

关联疾病

疾病名称 别名
Pancreatic Cystadenoma

Cystadenoma Of Pancreas

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta NIT1 VGNC VGNC:75351
Rattus norvegicus NIT1 RGD RGD:727821
Felis catus NIT1 VGNC VGNC:107904
Canis familiaris NIT1 VGNC VGNC:53123
Bos taurus NIT1 VGNC VGNC:32089
Mus musculus NIT1 MGD MGI:1350916
Others NIT1 NCBI