Rad51c - RAD51 paralog C Gene

种属: Rattus norvegicus

同用名: RGD1563765

关于 Rad51c

功能概要

Predicted to enable ATP binding activity and ATP-dependent activity, acting on DNA. Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Predicted to be involved in DNA recombination and positive regulation of G2/M transition of mitotic cell cycle. Predicted to act upstream of or within female meiosis sister chromatid cohesion; male meiosis I; and spermatogenesis. Predicted to be located in several cellular components, including mitochondrion; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex and Rad51C-XRCC3 complex. Predicted to be active in replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group O and hereditary breast ovarian Cancer syndrome. Orthologous to human RAD51C (RAD51 paralog C). [provided by Alliance of Genome Resources, Apr 2022]