Tnfrsf11a - TNF receptor superfamily member 11A Gene

中文名称：TNF 受体超家族成员 11A

种属: Rattus norvegicus

同用名: RANK; RGD1563614

关于 Tnfrsf11a

功能概要

预测该基因编码的蛋白编码的蛋白可启动细胞因子结合活性和肿瘤坏死因子激活受体活性。参与对辐射的反应。预测位于细胞表面；胞质溶胶；和质膜。预计在质膜外侧活跃。心肌炎的生物标志物。该基因的人类直系同源物与佩吉特骨病有关；常染色体隐性骨硬化症 7；骨发育疾病；家族性膨胀性骨质溶解；和骨质疏松症。与人类 TNFRSF11A（TNF 受体超家族成员 11a）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cytokine binding activity and tumor necrosis factor-activated receptor activity. Involved in response to radiation. Predicted to be located in cell surface; cytosol; and plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of myocarditis. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; familial expansile osteolysis; and osteoporosis. Orthologous to human TNFRSF11A (TNF Receptor Superfamily member 11a). [provided by Alliance of Genome Resources, Apr 2022]