1. Gene
  2. TAS2R14 - taste 2 receptor member 14 Gene

TAS2R14 - taste 2 receptor member 14 Gene

中文名称:味觉 2 受体成员 14

种属: Homo sapiens

同用名: TRB1; T2R14

基因 ID: 50840 | 基因类型: protein coding

关于 TAS2R14

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,937,410-10,939,263 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 224 orthologues and 23 paralogues.

功能概要

该基因产物属于候选味觉受体家族,是 G 蛋白偶联受体超家族的成员。这些蛋白质在舌头和上颚上皮细胞的味觉受体细胞中特异性表达。它们以簇的形式组织在基因组中,并与影响小鼠和人类苦味感知的基因座有遗传联系。在功能表达研究中,它们对促苦味剂有反应。该基因映射到染色体 12p13 上的味觉受体基因簇。[RefSeq 提供,2008 年 7 月]

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the Taste Receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the Taste Receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

TAS2R14 基因产物(1)

mRNA Protein Name
NM_023922.2 NP_076411.1 taste receptor type 2 member 14

TAS2R14 蛋白结构

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 298)

  • 0
  • 100
  • 200
  • 317 a.a.
蛋白主名 其他名称

taste receptor type 2 member 14

taste receptor, family B, member 1

关联疾病

疾病名称 别名
Angular Cheilitis

Cheilosis

Angular Cheilosis

Angular Stomatitis

Commissural Cheilitis

Parotid Disease

Parotid Diseases

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TAS2R14 RGD RGD:2314261