1. Gene
  2. LARP1B - La ribonucleoprotein 1B Gene

LARP1B - La ribonucleoprotein 1B Gene

中文名称:核糖核蛋白 1B

种属: Homo sapiens

同用名: LARP2

基因 ID: 55132 | 基因类型: protein coding

关于 LARP1B

This gene has 15 transcripts (splice variants), 218 orthologues and 6 paralogues. Broad expression in testis (RPKM 13.1), liver (RPKM 5.0) and 25 other tissues.

功能概要

该基因编码的蛋白质包含在黑腹果蝇的 La 相关蛋白质中发现的结构域。含有 La 基序的蛋白质被认为是 RNA 结合蛋白,其中 La 基序和相邻氨基酸折叠成 RNA 识别基序。 La 基序也存在于与 La 蛋白无关的蛋白质中。已在该位点观察到可变剪接,并描述了编码不同亚型的多个变体。已识别出额外的剪接变异,但尚未确定这些转录本的全长性质。[RefSeq 提供,2013 年 6 月]

This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent Amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]

LARP1B 基因产物(6)

mRNA Protein Name
NM_001278604.2 NP_001265533.1 la-related protein 1B isoform 4
NM_001350531.2 NP_001337460.1 la-related protein 1B isoform 5
NM_001410786.1 NP_001397715.1 la-related protein 1B isoform 6
NM_018078.4 NP_060548.2 la-related protein 1B isoform 1
NM_032239.4 NP_115615.2 la-related protein 1B isoform 3
NM_178043.3 NP_835144.1 la-related protein 1B isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LARP1B 蛋白结构

La

La: La domain (219 - 276)

  • 0
  • 200
  • 400
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  • 800
  • 914 a.a.
蛋白主名 其他名称

la-related protein 1B

La ribonucleoprotein domain family member 1B

LARP1B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra LARP1B Q659C4 KIF2A Homo sapiens O00139
Y2H Prey Pooling
25416956
Intra LARP1B Q659C4 KIF2A Homo sapiens O00139
Validated Y2H
25416956
Intra LARP1B Q659C4 TRIM69 Homo sapiens Q86WT6
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Mus musculus LARP1B MGD MGI:1914604
Bos taurus LARP1B VGNC VGNC:30791
Canis familiaris LARP1B VGNC VGNC:42588
Rattus norvegicus LARP1B RGD RGD:1307509
Macaca mulatta LARP1B VGNC VGNC:74115
Felis catus LARP1B VGNC VGNC:82486