2. Gene
  3. TMEM39A - transmembrane protein 39A Gene

TMEM39A - transmembrane protein 39A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜蛋白 39A

种属: Homo sapiens

同用名: SUSR2

基因 ID: 55254 | 基因类型: protein coding

关于 TMEM39A

This gene has 12 transcripts (splice variants), 210 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 7.9), placenta (RPKM 6.8) and 25 other tissues.

功能概要

参与自噬体组装的负调控；自噬体成熟的负调控；和病毒基因组复制的正调控。位于内质网膜上。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of viral genome replication. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM39A 基因产物(1)

mRNA Protein Name
NM_018266.3 NP_060736.1 transmembrane protein 39A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31806350 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of autophagosome assembly IMP
IMP: 通过突变表型推断
31806350 GOA
involved in negative regulation of autophagosome maturation IMP
IMP: 通过突变表型推断
31806350 GOA
involved in positive regulation of viral genome replication IDA
IDA: 通过直接分析推断
31849860 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
31806350 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TMEM39A 蛋白结构

Tmp39

Tmp39: Putative transmembrane protein (41 - 478)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 488 a.a.
蛋白主名 其他名称

transmembrane protein 39A

suppressor of SQST-1 aggregates in rpl-43 mutants

关联疾病

疾病名称 别名
Dowling-Degos Disease

Reticular Pigment Anomaly Of Flexures

Dark Dot Disease

Reticulate Acropigmentation Of Kitamura

Dowling-Degos Kitamura Disease

Kitamura Reticulate Acropigmentation

Ddd

Dowling-Degos-Kitamura Disease

Reticular Pigmented Anomaly Of Flexures
Adams-Oliver Syndrome

Adams Oliver Syndrome

Aos

Congenital Scalp Defects With Distal Limb Reduction Anomalies

Aplasia Cutis Congenita With Terminal Transverse Limb Defects

Congenital Scalp Defects With Distal Limb Anomalies

Limb, Scalp And Skull Defects

Limb Scalp And Skull Defects

Absence Defect Of Limbs, Scalp, And Skull
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14721 TMEM39A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus TMEM39A VGNC VGNC:66343
Macaca mulatta TMEM39A VGNC VGNC:79517
Canis familiaris TMEM39A VGNC VGNC:47576
Bos taurus TMEM39A VGNC VGNC:36082
Rattus norvegicus TMEM39A RGD RGD:1306421
Mus musculus TMEM39A MGD MGI:1915096
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