2. Gene
  3. RGS16 - regulator of G protein signaling 16 Gene

RGS16 - regulator of G protein signaling 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白信号调节器 16

种属: Homo sapiens

同用名: RGS-R; A28-RGS14; A28-RGS14P

基因 ID: 6004 | 基因类型: protein coding

关于 RGS16

Cytogenetic location: 1q25.3 Genomic coordinates (GRCh38): 1:182,598,623-182,604,389 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 23 paralogues. Biased expression in thyroid (RPKM 20.2), lung (RPKM 3.6) and 11 other tissues.

功能概要

该基因编码的蛋白质属于“G 蛋白信号调节因子”家族。它通过增加 G 蛋白 α 亚基的 GTP 酶活性来抑制信号转导。它还可能在调节光转导级联中的信号动力学方面发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

RGS16 基因产物(2)

mRNA Protein Name
XM_024448796.1 XP_024304564.1 regulator of G-protein signaling 16 isoform X1
NM_002928.4 NP_002919.3 regulator of G-protein signaling 16

RGS16 蛋白结构

RGS

RGS: Regulator of G protein signaling domain (65 - 179)

  • 0
  • 100
  • 202 a.a.
蛋白主名 其他名称

regulator of G-protein signaling 16

hRGS-r

regulator of G-protein signalling 16

retinal-specific RGS

retinally abundant regulator of G-protein signaling

关联疾病

疾病名称 别名
Retinitis Pigmentosa 12

RP12

Retinitis Pigmentosa With Or Without Paraarteriolar Preservation Of Retinal Pigment Epithelium

Rp With Or Without Preserved Paraarteriole Retinal Pigment Epithelium

Rp With Or Without Pprpe

Retinitis Pigmentosa-12
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13509 CCG-50014 Inhibitor 99.42% 否
HY-U00431 CCG 203769 Inhibitor 99.76% 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RGS16 MGD MGI:108407
Macaca mulatta RGS16 VGNC VGNC:76919
Canis familiaris RGS16 VGNC VGNC:45525
Rattus norvegicus RGS16 RGD RGD:1589741
Felis catus RGS16 VGNC VGNC:107931
Bos taurus RGS16 VGNC VGNC:33915
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