CCL14 - C-C motif chemokine ligand 14 Gene

中文名称：CC 基序趋化因子配体 14

种属: Homo sapiens

同用名: CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3

关于 CCL14

功能概要

该基因，趋化因子 (CC 基序) 配体 14，是聚集在 17q11.2 上的几个 CC 细胞因子基因之一。 CC 细胞因子是以两个相邻的半胱氨酸为特征的分泌蛋白。由该基因编码的细胞因子诱导单核细胞中细胞内钙浓度和酶释放的变化。已发现该基因编码不同异构体的多个转录变体。还表达了通读转录本，其中包括来自上游细胞因子基因、趋化因子 (CC 基序) 配体 15 的外显子，并表示为 GeneID：348249。[RefSeq 提供，2009 年 12 月]

This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and Enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]