2. Gene
  3. PIRT - phosphoinositide interacting regulator of transient receptor potential channels Gene

PIRT - phosphoinositide interacting regulator of transient receptor potential channels Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：瞬时受体电位通道的磷酸肌醇相互作用调节因子

种属: Homo sapiens

基因 ID: 644139 | 基因类型: protein coding

关于 PIRT

Cytogenetic location: 17p12 Genomic coordinates (GRCh38): 17:10,822,470-10,838,087 (from NCBI)

This gene has 1 transcript (splice variant), 109 orthologues and 1 paralogue. Biased expression in adrenal (RPKM 1.6), brain (RPKM 1.3) and 7 other tissues.

功能概要

预测可启用磷脂酰肌醇二磷酸结合活性和跨膜转运蛋白结合活性。预计参与磷脂酰肌醇介导的信号传导和阳离子通道活性的正调节。预计在对疼痛和对热的反应的行为反应的上游或内部起作用。预计是膜的组成部分。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable phosphatidylinositol bisphosphate binding activity and transmembrane transporter binding activity. Predicted to be involved in phosphatidylinositol-mediated signaling and positive regulation of cation channel activity. Predicted to act upstream of or within behavioral response to pain and response to heat. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PIRT 基因产物(1)

mRNA Protein Name
NM_001101387.2 NP_001094857.1 phosphoinositide-interacting protein

PIRT 蛋白结构

PIRT

PIRT: Phosphoinositide-interacting protein family (5 - 136)

  • 0
  • 100
  • 137 a.a.
蛋白主名 其他名称

phosphoinositide-interacting protein

phosphoinositide-interacting regulator of TRPV1

关联疾病

疾病名称 别名
Spastic Paraplegia 50, Autosomal Recessive

Hereditary Spastic Paraplegia 50

SPG50

Ap-4 Deficiency Syndrome

Ap-4-Associated Hereditary Spastic Paraplegia

Adaptor Protein Complex 4 Deficiency

Cerebral Palsy, Spastic Quadriplegic, 3, Formerly

Cpsq3, Formerly

Autosomal Recessive Spastic Paraplegia 50

Cpsq3

Spastic Quadriplegic Cerebral Palsy 3

Ap-4 Deficiency

Ap-4-Associated Hsp

Paraplegia, Spastic, Autosomal Recessive, Type 50

Spastic Paraplegia-50, Autosomal Recessive
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10572 PIRT Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PIRT MGD MGI:2443635
Bos taurus PIRT VGNC VGNC:32916
Canis familiaris PIRT VGNC VGNC:44580
Felis catus PIRT VGNC VGNC:99318
Rattus norvegicus PIRT RGD RGD:1565284
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