RANBP17 - RAN binding protein 17 Gene

中文名称：RAN 结合蛋白 17

种属: Homo sapiens

关于 RANBP17

功能概要

蛋白质和大分子 RNA 通过核孔复合体 (NPC) 的转运是一个能量依赖和受调节的过程。具有核定位信号 (NLS) 的蛋白质的输入是通过输入蛋白-α/β 复合物识别一个或多个碱性氨基酸簇来完成的；参见 MIM 600685 和 MIM 602738。小 GTP 酶 RAN (MIM 601179) 在 NLS 依赖性蛋白质导入中起着关键作用。 RAN 结合蛋白 17 是核转运受体 importin-beta 超家族的成员。[OMIM 提供，2002 年 7 月]

The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic Amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]