2. Gene
  3. OCM - oncomodulin Gene

OCM - oncomodulin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：癌调节素

种属: Homo sapiens

同用名: OM; OCM1; ONCM

基因 ID: 654231 | 基因类型: protein coding

关于 OCM

Cytogenetic location: 7p22.1 Genomic coordinates (GRCh38): 7:5,859,718-5,886,363 (from NCBI)

This gene has 2 transcripts (splice variants), 148 orthologues and 2 paralogues. Low expression observed in reference dataset.

功能概要

Oncomodulin 是一种高亲和力的钙离子结合蛋白。它属于钙调蛋白超家族，也称为 EF-hand 蛋白。 Oncomodulin 是一种肿瘤发育蛋白，存在于胎盘和肿瘤的早期胚胎细胞中。[RefSeq 提供，2008 年 7 月]

Oncomodulin is a high-affinity calcium ion-binding protein. It belongs to the superfamily of Calmodulin proteins, also known as the EF-hand proteins. Oncomodulin is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors. [provided by RefSeq, Jul 2008]

OCM 基因产物(3)

mRNA Protein Name
NM_001097622.2 NP_001091091.1 oncomodulin-1 isoform a
NM_001391990.1 NP_001378919.1 oncomodulin-1 isoform a
NM_001391991.1 NP_001378920.1 oncomodulin-1 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

OCM 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (43 - 106)

  • 0
  • 100
  • 109 a.a.
蛋白主名 其他名称

oncomodulin-1

beta parvalbumin

OCM 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
OCM P0CE72 CKMT1A Homo sapiens P12532
Y2H Array
32296183
种属内
OCM P0CE72 CKMT1A Homo sapiens P12532
MAPPIT
32296183
种属内
OCM P0CE72 CKMT1A Homo sapiens P12532
Y2H Prey Pooling
32296183
种属内
OCM P0CE72 CKMT1A Homo sapiens P12532
Validated Y2H
32296183
种属内
OCM P0CE72 SDCBP Homo sapiens O00560
Y2H Prey Pooling
32296183
种属内
OCM P0CE72 SDCBP Homo sapiens O00560
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 OCM 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71100 Oncomodulin-1 Protein, Human (His) P0CE72 (M1-S109) ≥95%

关联疾病

疾病名称 别名
Fish Allergy

Allergy To Fish
Vulvar Leiomyoma
Vulvar Benign Neoplasm
Vegetable Allergy
Capillary Malformations, Congenital

Familial Multiple Nevi Flammei

Nevi Flammei, Familial Multiple

CMC

Port-Wine Stain

Capillary Malformations

Cmal

Familial Multiple Port-Wine Stains

Capillary Malformation

Capillary Malformations, Congenital, 1, Somatic, Mosaic

Congenital Capillary Malformations

Port-Wine Stain Familial Multiple

Hereditary Capillary Malformations

Capillary Malformations, Hereditary

Capillary Malformations, Congenital, Type 1, Somatic, Mosaic

Strawberry Nevus Of Skin

Naevus Flammeus
Bartholin'S Duct Cyst

Bartholin Duct Cyst

Bartholin'S Cyst

Cyst Of Bartholin'S Gland Duct

Cyst Of Bartholin'S Gland

Vulvovaginal Cyst

Cyst Of Bartholin Gland Duct
Deafness, Autosomal Dominant 27

DFNA27

Autosomal Dominant Nonsyndromic Deafness 27

Autosomal Dominant Deafness 27

Deafness, Autosomal Dominant, 27
Enterobiasis

Oxyuriasis

Pinworm Infection

Enterobius Vermicularis Infection

Threadworm Infection

Oxyuris Vermicularis Infection

Enterobiosis

Pinworm

Pinworm Disease

Seatworm Infection

Enterobiasis Threadworm

Pinworm Infestation

Seatworm
Vulvar Leiomyosarcoma
Deafness, Autosomal Dominant 50

DFNA50

Autosomal Dominant Nonsyndromic Deafness 50

Autosomal Dominant Deafness 50

Deafness, Autosomal Dominant, Type 50
Acute Hemorrhagic Leukoencephalitis

Ahl

Acute Haemorrhagic Leucoencephalitis Of Weston Hurst

Leukoencephalitis, Acute Hemorrhagic

Acute Hemorrhagic Encephalomyelitis

Acute Necrotizing Hemorrhagic Leukoencephalitis

Weston-Hurst Syndrome

Ahle

Acute Haemorrhagic Leucoencephalitis

Hurst Disease

Acute Haemorrhagic Leukoencephalitis, Postimmunization Or Postvaccinal

Postimmunization Or Postvaccinal Leukoencephalopathy
Vertigo, Benign Recurrent

Benign Paroxysmal Positional Vertigo

Bppv

Vestibulopathy, Familial

BRV

Vertigo, Benign Paroxysmal Positional

Benign Paroxysmal Positional Nystagmus

Benign Recurrent Vertigo

Familial Benign Recurrent Vertigo

Familial Vestibulopathy

Benign Paroxysmal Nystagmus

Bppv - [Benign Positional Paroxysmal Vertigo]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09744 OCM Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09745 OCM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus OCM MGD MGI:97401
Rattus norvegicus OCM RGD RGD:3222
Others OCM NCBI
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