INS-IGF2 - INS-IGF2 readthrough Gene

中文名称：INS-IGF2 通读

种属: Homo sapiens

同用名: INSIGF

基因 ID: 723961 | 基因类型: protein coding

关于 INS-IGF2

This gene has 2 transcripts (splice variants). Biased expression in placenta (RPKM 1227.5) and liver (RPKM 104.8).

功能概要

该基因座包括两个可变剪接的通读转录本变体，它们与 5' 区域的 INS 基因和 3' 区域的 IGF2 基因对齐。预测一个转录物编码一种蛋白质，该蛋白质与 INS 蛋白共享 N 末端，但具有明显且更长的 C 末端，而另一个转录物是无义介导衰变 (NMD) 的候选者。转录物被印记并在肢体和眼睛中以父亲的方式表达。[RefSeq 提供，2008 年 7 月]

This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]

INS-IGF2 基因产物(1)

mRNA	Protein	Name
NM_001042376.3	NP_001035835.1	insulin, isoform 2 precursor

INS-IGF2 蛋白结构

Insulin

0
100
200 a.a.

蛋白主名

其他名称

insulin, isoform 2

INS-IGF2 readthrough transcript protein

关联疾病

疾病名称

别名

Maturity-Onset Diabetes Of The Young, Type 10

Maturity-Onset Diabetes Of The Young Type 10	MODY10
Maturity-Onset Diabetes Of The Young 10	Mody-10
Mody Type 10	Diabetes Of The Young, Maturity-Onset, Type 10

Silver-Russell Syndrome 3

Growth Restriction, Severe, With Distinctive Facies	SRS3
Grdf

Diabetes Mellitus, Permanent Neonatal, 4

Diabetes Mellitus, Permanent Neonatal 4	PNDM4
Diabetes Mellitus, Permanent Neonatal, Type 4

Hyperproinsulinemia

HPRI

Type 1 Diabetes Mellitus 2

Diabetes Mellitus, Noninsulin-Dependent, 1	Diabetes Mellitus, Insulin-Dependent, 2
IDDM2	Insulin-Dependent Diabetes Mellitus 2
NIDDM1	Diabetes Mellitus, Noninsulin-Dependent 1
T1D2	Type 2 Diabetes Mellitus 1
T2D1	Noninsulin-Dependent Diabetes Mellitus 1
Diabetes Mellitus, Non-Insulin-Dependent, 1	Type 2 Diabetes Mellitus 1, Susceptibility To
Diabetes Mellitus, Insulin-Dependent, Type 2	Diabetes Mellitus, Non-Insulin-Dependent

Diabetes Mellitus, Permanent Neonatal, 1

PNDM1	Pdmi
Dend Syndrome	Permanent Diabetes Mellitus Of Infancy
Permanent Neonatal Diabetes Mellitus 1	Diabetes Mellitus, Permanent, Of Infancy
Diabetes Mellitus, Permanent Neonatal 1	Developmental Delay-Epilepsy-Neonatal Diabetes Syndrome
Dend	Developmental Delay Epilepsy And Neonatal Diabetes
Diabetes Mellitus Permanent Neonatal With Neurologic Features	Diabetes Mellitus, Permanent Neonatal, Type 1

Silver-Russell Syndrome 1

Silver-Russell Syndrome	Russell-Silver Syndrome
Silver-Russell Dwarfism	Rss
SRS1	Srs
Silver Russell Dwarfism	Russell Silver Syndrome
Silver Russell Syndrome

Permanent Neonatal Diabetes Mellitus

Pndm	Permanent Diabetes Mellitus Of Infancy
Pdmi	Neonatal Diabetes Mellitus, Permanent

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Neonatal Diabetes

Neonatal Diabetes Mellitus	Diabetes Mellitus Syndrome In Newborn Infant
Ndm

Monogenic Diabetes

Maturity-Onset Diabetes Of The Young

MODY	Maturity Onset Diabetes Mellitus In Young
Mason-Type Diabetes	Mason Type Diabetes
Maturity Onset Diabetes Of The Young	Mody Syndrome
Diabetes Of The Young, Maturity-Onset

Diabetes Mellitus

Diabetes

Retroperitoneum Carcinoma

Retroperitoneal Cancer	Malignant Neoplasm Of Retroperitoneum And Peritoneum
Retroperitoneal Neoplasms	Carcinoma Of Retroperitoneum
Carcinoma Of The Retroperitoneum	Malignant Neoplasm Of Retroperitoneum
Malignant Retroperitoneal Cancer	Malignant Tumor Of Peritoneum And Retroperitoneum
Neoplasm Of Retroperitoneum	Neoplasm Of The Retroperitoneum
Retroperitoneal Neoplasm	Tumor Of Retroperitoneum
Malignant Retroperitoneal Tumour	Primary Malignant Neoplasm Of Retroperitoneum
Retroperitoneum Cancer

Beckwith-Wiedemann Syndrome

Wiedemann-Beckwith Syndrome	BWS
Exomphalos-Macroglossia-Gigantism Syndrome	Emg Syndrome
Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation	Emg Abnormality
Wbs	Exomphalos Macroglossia Gigantism Syndrome
Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation	Macroglossia Exomphalos Gigantism

Adult Syndrome

Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome	Acro Dermato Ungual Lacrimal Tooth Syndrome
Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome	Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome
Adult

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06839	INS-IGF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	INS-IGF2	RGD	RGD:2915

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

INS-IGF2 - INS-IGF2 readthrough Gene

关于 INS-IGF2

功能概要

INS-IGF2 基因产物(1)

INS-IGF2 蛋白结构

关联疾病

直系同源

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INS-IGF2 - INS-IGF2 readthrough Gene

关于 INS-IGF2

功能概要

INS-IGF2 基因产物(1)

INS-IGF2 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

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Q

S

T

X

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