1. Gene
  2. Vsir - V-set immunoregulatory receptor Gene

Vsir - V-set immunoregulatory receptor Gene

种属: Mus musculus

同用名: Dies1; PD-1H; VISTA; 4632428N05Rik

基因 ID: 74048 | 基因类型: protein coding

关于 Vsir

功能概要

Predicted to enable endopeptidase activator activity; Enzyme binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of T cell cytokine production; and positive regulation of BMP signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including heart; immune system; lung; male reproductive gland or organ; and small intestine lamina propria. Orthologous to human VSIR (V-set immunoregulatory receptor). [provided by Alliance of Genome Resources, Apr 2022]

Vsir 基因产物(2)

mRNA Protein Name
NM_001159572.1 NP_001153044.1 V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 2 precursor
NM_028732.4 NP_083008.1 V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20042595 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
20042595 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
20042595 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

V-type immunoglobulin domain-containing suppressor of T-cell activation

V-set domain-containing immunoregulatory receptor

differentiation of ESCs 1

platelet receptor Gi24

重组 Vsir 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72428 VISTA/B7-H5 Protein, Mouse (159a.a, HEK293, His) Q9D659 (F33-A191) ≥95%
HY-P73547 VISTA/B7-H5 Protein, Mouse (HEK293, Fc) Q9D659 (F33-A194) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vsir NCBI NCBI:64115