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  2. GPR157 - G protein-coupled receptor 157 Gene

GPR157 - G protein-coupled receptor 157 Gene

中文名称:G 蛋白偶联受体 157

种属: Homo sapiens

基因 ID: 80045 | 基因类型: protein coding

关于 GPR157

This gene has 3 transcripts (splice variants), 188 orthologues and 1 paralogue. Broad expression in esophagus (RPKM 10.7), skin (RPKM 5.0) and 22 other tissues.

功能概要

预计可启用 G 蛋白偶联受体活性。预计参与正调节细胞溶质钙离子浓度,参与磷脂酶 C 激活 G 蛋白偶联信号通路和放射状神经胶质细胞分化。预测位于睫状膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway and radial glial cell differentiation. Predicted to be located in ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR157 基因产物(1)

mRNA Protein Name
NM_024980.5 NP_079256.4 G-protein coupled receptor 157

GPR157 蛋白结构

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (18 - 236)

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  • 335 a.a.
蛋白主名 其他名称

G-protein coupled receptor 157

probable G-protein coupled receptor 157

关联疾病

疾病名称 别名
Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy

SCCD

Corneal Dystrophy, Crystalline, Of Schnyder

Corneal Dystrophy, Schnyder Type

Corneal Dystrophy Crystalline Of Schnyder

Crystalline Stromal Dystrophy

Hereditary Crystalline Stromal Dystrophy Of Schnyder

Scd

Corneal Dystrophy, Schnyder

Schnyder Crystalline Dystrophy Sine Crystals

Dystrophy, Corneal, Crystalline, Schnyder

Nephrogenic Syndrome Of Inappropriate Antidiuresis

NSIAD

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GPR157 VGNC VGNC:41409
Felis catus GPR157 VGNC VGNC:62682
Rattus norvegicus GPR157 RGD RGD:1311096
Bos taurus GPR157 VGNC VGNC:29563
Mus musculus GPR157 MGD MGI:2442046
Macaca mulatta GPR157 VGNC VGNC:106376