PDGFD - platelet derived growth factor D Gene

中文名称：血小板衍生生长因子 D

种属: Homo sapiens

同用名: IEGF; SCDGFB; MSTP036; SCDGF-B

关于 PDGFD

功能概要

该基因编码的蛋白质是血小板衍生生长因子家族的一员。该家族的四个成员是间充质起源细胞的促有丝分裂因子，其特征是八个半胱氨酸的核心基序，其中七个在该因子中发现。该基因产物仅形成同型二聚体，因此不会与其他三个家族成员二聚化。它不同于该家族的 alpha 和 beta 成员，因为它有一个不寻常的 N 末端域，即 CUB 域。已经为该基因鉴定了两个剪接变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the Other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]