1. Gene
  2. AIF1L - allograft inflammatory factor 1 like Gene

AIF1L - allograft inflammatory factor 1 like Gene

中文名称:同种异体移植炎症因子 1

种属: Homo sapiens

同用名: IBA2; C9orf58

基因 ID: 83543 | 基因类型: protein coding

关于 AIF1L

This gene has 10 transcripts (splice variants), 199 orthologues and 1 paralogue. Biased expression in kidney (RPKM 130.1), spleen (RPKM 121.3) and 8 other tissues.

功能概要

启用肌动蛋白丝结合活性。预计参与肌动蛋白丝束组装和荷叶边组装。位于肌动蛋白细胞骨架和粘着斑中。与肌动蛋白丝共定位。乳腺癌的生物标志物。 [由基因组资源联盟提供,2022 年 4 月]

Enables actin filament binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Located in actin Cytoskeleton and focal adhesion. Colocalizes with actin filament. Biomarker of breast Cancer. [provided by Alliance of Genome Resources, Apr 2022]

AIF1L 基因产物(3)

mRNA Protein Name
NM_001185095.2 NP_001172024.1 allograft inflammatory factor 1-like isoform 3
NM_001185096.2 NP_001172025.1 allograft inflammatory factor 1-like isoform 4
NM_031426.4 NP_113614.1 allograft inflammatory factor 1-like isoform 1
蛋白主名 其他名称

allograft inflammatory factor 1-like

ionized calcium binding adapter molecule 2

关联疾病

疾病名称 别名
Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma

Adenoid Cystic Carcinoma Of The Skin

Adenoid Cystic Eccrine Carcinoma Of Skin

Bronchus Cancer

Malignant Neoplasm Of Bronchus And Lung

Bronchus Carcinoma

Bronchogenic Carcinoma

Malignant Neoplasm Of Bronchus Or Lung

Bc - Bronchogenic Carcinoma

Carcinoma, Bronchogenic

Bronchial Neoplasms

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus AIF1L VGNC VGNC:25760
Felis catus AIF1L VGNC VGNC:102896
Mus musculus AIF1L MGD MGI:1919598
Rattus norvegicus AIF1L RGD RGD:1305081
Macaca mulatta AIF1L VGNC VGNC:103237
Canis familiaris AIF1L VGNC VGNC:37736