1. Gene
  2. OR1A1 - olfactory receptor family 1 subfamily A member 1 Gene

OR1A1 - olfactory receptor family 1 subfamily A member 1 Gene

中文名称:嗅觉受体家族 1 亚科 A 成员 1

种属: Homo sapiens

同用名: OR17-7

基因 ID: 8383 | 基因类型: protein coding

关于 OR1A1

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:3,207,667-3,218,896 (from NCBI)

This gene has 3 transcripts (splice variants), 169 orthologues and 130 paralogues.

功能概要

嗅觉受体与鼻子中的气味分子相互作用,引发神经元反应,从而触发对气味的感知。嗅觉受体蛋白是来自单个编码外显子基因的 G 蛋白偶联受体 (GPCR) 大家族的成员。嗅觉受体与许多神经递质和激素受体共享一个 7 跨膜结构域,负责气味信号的识别和 G 蛋白介导的转导。嗅觉受体基因家族是基因组中最大的。分配给该生物体的嗅觉受体基因和蛋白质的命名法独立于其他生物体。[RefSeq 提供,2008 年 7 月]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory Receptor Proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

OR1A1 基因产物(2)

mRNA Protein Name
NM_001386104.1 NP_001373033.1 olfactory receptor 1A1
NM_014565.3 NP_055380.2 olfactory receptor 1A1

OR1A1 蛋白结构

7tm_4

7tm_4: Olfactory receptor (140 - 281)

  • 0
  • 100
  • 200
  • 309 a.a.
蛋白主名 其他名称

olfactory receptor 1A1

olfactory receptor 17-7

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus OR1A1 RGD RGD:1332685