1. Gene
  2. PRSS27 - serine protease 27 Gene

PRSS27 - serine protease 27 Gene

中文名称:丝氨酸蛋白酶 27

种属: Homo sapiens

同用名: MPN; CAPH2

基因 ID: 83886 | 基因类型: protein coding

关于 PRSS27

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,712,422-2,720,224 (from NCBI)

This gene has 5 transcripts (splice variants), 123 orthologues and 14 paralogues. Biased expression in esophagus (RPKM 55.3) and skin (RPKM 0.9).

功能概要

该基因位于 16 号染色体上的一个大蛋白酶基因簇内。它属于丝氨酸蛋白酶的第 1 组亚家族。编码的蛋白质是一种分泌型胰蛋白酶丝氨酸蛋白酶,主要在胰腺中表达。可变剪接导致多个转录本变体。[RefSeq 提供,2016 年 1 月]

This gene is located within a large protease gene cluster on chromosome 16. It belongs to the group-1 subfamily of serine proteases. The encoded protein is a secreted tryptic serine protease and is expressed mainly in the pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

PRSS27 基因产物(2)

mRNA Protein Name
NM_001318395.2 NP_001305324.1 serine protease 27 isoform 2
NM_031948.5 NP_114154.1 serine protease 27 isoform 1 precursor

PRSS27 蛋白结构

Trypsin

Trypsin: Trypsin (36 - 272)

  • 0
  • 100
  • 200
  • 290 a.a.
蛋白主名 其他名称

serine protease 27

channel-activating protease 2

重组 PRSS27 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77077 Marapsin/Pancreasin Protein, Human (HEK293, His) Q9BQR3 (A23-K290) ≥95%

关联疾病

疾病名称 别名
Necrotizing Gastritis
Melnick-Needles Syndrome

MNS

Melnick-Needles Osteodysplasty

Osteodysplasty Of Melnick And Needles

Osteochondrodysplasias

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus PRSS27 VGNC VGNC:33417
Rattus norvegicus PRSS27 RGD RGD:1303256
Mus musculus PRSS27 MGD MGI:2450123
Felis catus PRSS27 VGNC VGNC:108374
Others PRSS27 NCBI