1. Gene
  2. FNDC1 - fibronectin type III domain containing 1 Gene

FNDC1 - fibronectin type III domain containing 1 Gene

中文名称:含纤连蛋白 III 型域 1

种属: Homo sapiens

同用名: AGS8; FNDC2; MEL4B3; bA243O10.1; dJ322A24.1

基因 ID: 84624 | 基因类型: protein coding

关于 FNDC1

Cytogenetic location: 6q25.3 Genomic coordinates (GRCh38): 6:159,169,400-159,272,108 (from NCBI)

This gene has 3 transcripts (splice variants), 200 orthologues and 1 paralogue. Biased expression in gall bladder (RPKM 10.5), thyroid (RPKM 9.5) and 12 other tissues.

功能概要

预计在几个过程的上游或内部起作用,包括细胞对缺氧的反应;心肌细胞凋亡过程的正调控;和蛋白质磷酸化的正调节。位于核斑点。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to act upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

FNDC1 基因产物(1)

mRNA Protein Name
NM_032532.3 NP_115921.2 fibronectin type III domain-containing protein 1 precursor

FNDC1 蛋白结构

fn3

fn3: Fibronectin type III domain (43 - 121)

fn3

fn3: Fibronectin type III domain (262 - 347)

fn3

fn3: Fibronectin type III domain (362 - 447)

fn3

fn3: Fibronectin type III domain (1658 - 1742)

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  • 1894 a.a.
蛋白主名 其他名称

fibronectin type III domain-containing protein 1

activation-associated cDNA protein

重组 FNDC1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700995 FNDC1 Protein, Human (His) Q4ZHG4-1 (A33-T457) ≥95%

关联疾病

疾病名称 别名
Prostate Leiomyosarcoma

Leiomyosarcoma Of The Prostate

Prostate Sarcoma

Sarcoma Of The Prostate

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta FNDC1 VGNC VGNC:72546
Bos taurus FNDC1 VGNC VGNC:58376
Mus musculus FNDC1 MGD MGI:1915905
Rattus norvegicus FNDC1 RGD RGD:1310640
Felis catus FNDC1 VGNC VGNC:82362
Canis familiaris FNDC1 VGNC VGNC:40927
Others FNDC1 NCBI