2. Gene
  3. UNC5A - unc-5 netrin receptor A Gene

UNC5A - unc-5 netrin receptor A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：unc-5 netrin 受体 A

种属: Homo sapiens

同用名: UNC5H1

基因 ID: 90249 | 基因类型: protein coding

关于 UNC5A

Cytogenetic location: 5q35.2 Genomic coordinates (GRCh38): 5:176,810,559-176,880,898 (from NCBI)

This gene has 3 transcripts (splice variants), 195 orthologues and 4 paralogues. Biased expression in brain (RPKM 7.1) and adrenal (RPKM 2.6).

功能概要

UNC5A 属于 netrin-1 (MIM 601614) 受体家族，被认为介导 netrin-1 对特定轴突的化学排斥作用。有关 UNC5 蛋白质的更多信息，请参阅 UNC5C (MIM 603610) 。[OMIM 提供，2004 年 4 月]

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]

UNC5A 基因产物(1)

mRNA Protein Name
NM_133369.3 NP_588610.2 netrin receptor UNC5A precursor

UNC5A 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (150 - 238)

ZU5

ZU5: ZU5 domain (441 - 540)

Death

Death: Death domain (763 - 832)

  • 0
  • 200
  • 400
  • 600
  • 842 a.a.
蛋白主名 其他名称

netrin receptor UNC5A

netrin receptor Unc5h1

重组 UNC5A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76692 UNC5H1 Protein, Human (HEK293, Fc) Q6ZN44-1/NP_588610.2 (Q26-Y306) ≥95%
HY-P76693 UNC5H1 Protein, Human (HEK293, His) Q6ZN44-1/NP_588610.2 (Q26-Y306) ≥95%

关联疾病

疾病名称 别名
Tonne-Kalscheuer Syndrome

TOKAS

Mrx61

Intellectual Developmental Disorder With Or Without Hand And Foot Anomalies, Genital Anomalies, Or Congenital Diaphragmatic Hernia

Mental Retardation, X-Linked 61

X-Linked Mental Retardation 61
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15471 UNC5A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris UNC5A VGNC VGNC:48139
Rattus norvegicus UNC5A RGD RGD:621755
Mus musculus UNC5A MGD MGI:894682
Felis catus UNC5A VGNC VGNC:66828
Bos taurus UNC5A VGNC VGNC:36670
Macaca mulatta UNC5A VGNC VGNC:78721
Others UNC5A NCBI
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