Prmt6 - protein arginine N-methyltransferase 6 Gene

中文名称：蛋白质精氨酸 N-甲基转移酶 6

种属: Mus musculus

同用名: Hrmt1l6

关于 Prmt6

功能概要

该基因编码的蛋白可启动染色质结合活性和组蛋白-精氨酸 N-甲基转移酶活性。参与肽基-精氨酸 N-甲基化。作用于多个过程的上游或内部，包括细胞衰老；组蛋白 H3-R2 甲基化；氮化合物代谢过程的负调控。预测位于核仁和核质中。表达于中枢神经系统和感觉器官。与人类 PRMT6（蛋白质精氨酸甲基转移酶 6）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables chromatin binding activity and histone-arginine N-methyltransferase activity. Involved in peptidyl-arginine N-methylation. Acts upstream of or within several processes, including cellular senescence; histone H3-R2 methylation; and negative regulation of nitrogen compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Is expressed in central nervous system and sensory organ. Orthologous to human PRMT6 (protein arginine methyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]