1. Anti-infection Cell Cycle/DNA Damage
  2. RSV DNA/RNA Synthesis
  3. GHP-88309

GHP-88309 是一种广谱的、口服有效抗副黏病毒 (paramyxoviruses) 剂,靶向病毒聚合酶 (viral polymerase),中断病毒 RNA 合成,并抑制呼吸道合胞病毒 (RSV)、麻疹病毒 (MeV) 和犬瘟热病毒 (CDV),EC50 为 0.06-1.2 μM。GHP-88309 在小鼠模型中表现出抗感染活性。

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GHP-88309 Chemical Structure

GHP-88309 Chemical Structure

CAS No. : 1269267-87-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models[1].

分子量

266.27

Formula

C16H11FN2O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GHP-88309
目录号:
HY-170395
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