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GK241 (compound 31a-c) 是一种基于2-氧代酰胺的化合物,具有对人及小鼠的IIA组分泌型磷脂酶A2(GIIA sPLA2)有抑制活性(IC50分别为143 nM和68 nM)的活性,且通过分子动力学模拟研究了其抑制机制。

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GK241 Chemical Structure

GK241 Chemical Structure

CAS No. : 1899930-93-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GK241 (compound 31a-c) is a 2-oxoamide-based compound that has inhibitory activity against human and mouse group IIA secretory phospholipase A2 (GIIA sPLA2) (IC50 of 143 nM and 68 nM, respectively), and its inhibitory mechanism was studied by molecular dynamics simulation.

分子量

369.54

Formula

C21H39NO4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

GK241 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GK241
目录号:
HY-158792
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