1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. [Glp5] Substance P (5-11)

[Glp5] Substance P (5-11) 是一种八肽。[Glp5] Substance P (5-11) 是大鼠中枢神经系统 (CNS) 主要 P 物质片段之一。[Glp5] Substance P (5-11) 局部调节大鼠纹状体多巴胺释放。

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Custom Peptide Synthesis

[Glp5] Substance P (5-11) Chemical Structure

[Glp5] Substance P (5-11) Chemical Structure

CAS No. : 56104-22-4

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生物活性

[Glp5] Substance P (5-11) is an octapeptide. [Glp5] Substance P (5-11) is one of the main substance P fragments in rat central nervous system (CNS). [Glp5] Substance P (5-11) locally modulates dopamine release in rat striatum[1].

体外研究
(In Vitro)

[Glp5] Substance P (5-11) (0.12 nM-10 μM; rat striatum) modifies spontaneous dopamine outflow with a significant increase in dopamine outflow at 0.1 nM and a smaller effect at 1 nM, whereas concentrations lower than 0.1 nM or higher than 1 nM failed to modify dopamine release. [Glp5] Substance P (5-11) and K+ has additive effect, promoting the release of dopamine[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

852.01

Formula

C41H57N9O9S

CAS 号
Sequence Shortening

Glp-QFFGLM-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
[Glp5] Substance P (5-11)
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