2. GPCR/G Protein
  3. GCGR
  4. Glucagon receptor antagonists-5

Glucagon receptor antagonists-5 

目录号: HY-128781
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Glucagon receptor antagonists-5 (compound 13K) 是一种有效的口服生物可利用的胰高血糖素受体 (glucagon receptor) 拮抗剂 (Ki=32 nM)。Glucagon receptor antagonists-5 具有研究 2 型糖尿病的潜力。

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Glucagon receptor antagonists-5 Chemical Structure

Glucagon receptor antagonists-5 Chemical Structure

CAS No. : 2200274-63-9

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Glucagon receptor antagonists-5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].

IC50 & Target

Ki: 32 nM (glucagon receptor)[1]
分子量

572.02

Formula

C30H29ClF3N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Glucagon receptor antagonists-5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glucagon receptor antagonists-52200274-63-9Glucagon receptor antagonists5Glucagon receptor antagonists 5GCGRGlucagon ReceptorInhibitorinhibitorinhibit

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