Glyphosate isopropylammonium  (Synonyms: 草甘膦异丙胺盐)

Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate isopropylammonium inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate isopropylammonium induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders^[1][2][3].

Glyphosate isopropylammonium 暴露可通过产生氧化应激和早期细胞凋亡来干扰小鼠卵母细胞的成熟。Glyphosate isopropylammonium 诱导小鼠卵母细胞的早期细胞凋亡和自噬^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

228.18

C₆H₁₇N₂O₅P

38641-94-0

草甘膦异丙胺盐

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208.  [Content Brief]

  [2]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435.  [Content Brief]

  [3]. Carmen Costas-Ferreira, et al. Toxic Effects of Glyphosate on the Nervous System: A Systematic Review. Int J Mol Sci. 2022 Apr 21;23(9):4605.  [Content Brief]