2. Immunology/Inflammation
  3. CD3
  4. Gresonitamab

Gresonitamab  (Synonyms: AMG 910; Anti-Human CD3xClaudin18 2)

目录号: HY-P99350 纯度: 99.12%
COA

摩尔计算器

Gresonitamab (AMG 910) 是一种半衰期延长 (HLE) 双特异性 T 细胞接合物 (BiTE) 抗体，靶向 CD3 阳性 T 细胞和表达 CLDN18.2 的肿瘤细胞。Gresonitamab 可用于腺癌的研究。

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CAS No. : 2413817-97-5

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规格 价格 是否有货 数量
1 mg ￥2500
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5 mg ￥8000
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Gresonitamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma[1].

同型

(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
种属

Human; Chimeric
体外研究
(In Vitro)

Gresonitamab 重定向肿瘤细胞裂解以杀死肿瘤细胞[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Gresonitamab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • (scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Biological Activity
  • Immobilized Gresonitamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 3.97 ng/mL.
纯度 & 产品资料

纯度: 99.12%

COA (172 KB) SDS-PAGE (566 KB) SEC-HPLC (678 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Gresonitamab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gresonitamab2413817-97-5AMG 910 Anti-Human CD3xClaudin18 2AMG910AMG-910CD3Cluster of differentiation 3BiTEHLEantibodyadenocarcinomaInhibitorinhibitorinhibit

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