2. Metabolic Enzyme/Protease
  3. FXR
  4. GSK2324

GSK2324 (Compd 1c) 是 FXR 的激动剂，可用于糖尿病研究，其 EC50 值为 120 nM。GSK2324 的半衰期分别为84 min (mouse)、170 min (rat)、110 min (beagle) 和 120 min (cyno)。

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GSK2324 Chemical Structure

GSK2324 Chemical Structure

CAS No. : 1020567-30-9

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规格 价格 是否有货
1 mg ￥5425
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GSK2324 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CV-1 EC50
50 nM
Compound: 1c, GSK2324
Agonist activity at human FXR LBD transfected in african green monkey CV1 cells after overnight incubation by luciferase reporter gene assay
Agonist activity at human FXR LBD transfected in african green monkey CV1 cells after overnight incubation by luciferase reporter gene assay
[PMID: 21890356]
分子量

533.40

Formula

C29H22Cl2N2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GSK2324 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK23241020567-30-9GSK 2324GSK-2324FXRNR1H4diabetesdiet-induced obese (DIO) mouseInhibitorinhibitorinhibit

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目录号：
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