2. Anti-infection Cell Cycle/DNA Damage
  3. HBV DNA/RNA Synthesis
  4. HBV-IN-22

HBV-IN-22 (Compound LC5f) 是一种 HBV DNA 复制抑制剂，对野生型和耐药 HBV 的 IC50 分别为 0.71 μM 和 0.84 μM。

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HBV-IN-22 Chemical Structure

HBV-IN-22 Chemical Structure

CAS No. : 2338573-94-5

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HBV-IN-22 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HBV-IN-22 (Compound LC5f) is an inhibitor of HBV DNA replication with IC50 values of 0.71 μM and 0.84 μM against wild-type and agent resistant HBV strains, respectively[1].

IC50 & Target

IC50: 0.71 µM (wild-type HBV DNA replication), 0.84 µM (drug resistant HBV DNA replication)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 2.2.15 CC50
> 10 μM
Compound: LC5f
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
[PMID: 35123297]
HepG2 2.2.15 CC50
15.79 μM
Compound: 5f
Cytotoxicity against human HepG2.2.15 cells assessed as cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2.2.15 cells assessed as cell viability measured after 72 hrs by MTT assay
[PMID: 31091479]
分子量

479.66

Formula

C26H29N3O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HBV-IN-22 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBV-IN-222338573-94-5HBVDNA/RNA SynthesisHepatitis B virusanti-HBVdrug resistant HBV strainInhibitorinhibitorinhibit

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