2. Anti-infection
  3. HBV
  4. HBV-IN-45

HBV-IN-45 是一种选择性、具有口服活性的 HBV 衣壳组装调节剂，对 HBC 细胞中的 HBcAg 的 IC50 为 0.51 μM。HBV-IN-45 显示出有效的抗 HBV 活性。

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HBV-IN-45 Chemical Structure

HBV-IN-45 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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100 mg   询价  
250 mg   询价  

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Customer Review

HBV-IN-45 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HBV-IN-45 is a selective and orally active HBV capsid assembly modulator with an IC50 of 0.51 μM for HBcAg in HBC cells. HBV-IN-45 shows potent anti-HBV activities[1].

体外研究
(In Vitro)

HBV-IN-45 (compound 26f) 抑制 HepG2 细胞的生长，CC50 值为 84.29 μM。HBV-IN-45 还可抑制 HepAD38 细胞上清液中的 HBV DNA，EC50 为 2.24 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HBV-IN-45 相关抗体:
体内研究
(In Vivo)

HBV-IN-45（compound 26f；100 mg/kg；口服；每日两次；持续14天）抑制血浆中 HBV DNA 数量，小鼠血清中 HBeAg 和肝酶 GPT（ALT）无差异[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male BALB/c mice injected with replication-competent HBV 1.3 DNA plasmid[1]
Dosage: 100 mg/kg
Administration: Oral administration; twice daily; for 14 days
Result: HBV DNA copy numbers were rapidly and markedly reduced in plasma.
分子量

300.38

Formula

C16H16N2O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HBV-IN-45 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBV-IN-45HBVHepatitis B virusHBV inhibitorHBV capsid assemblyHBcAgInhibitorinhibitorinhibit

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目录号：
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