2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC-IN-72

HDAC-IN-72 (compound 7j) 是较好的 HDAC1 (IC50=0.65 μM)，HDAC2 (IC50=0.78 μM)，HDAC3 (IC50=1.70 μM) 抑制剂和抗增殖化合物。HDAC-IN-72 可用于乳腺癌的研究。

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HDAC-IN-72 Chemical Structure

HDAC-IN-72 Chemical Structure

CAS No. : 763066-77-9

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HDAC-IN-72 相关抗体

Top Publications Citing Use of Products

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research[1].

IC50 & Target

HDAC1

0.65 μM (IC50)

HDAC2

0.78 μM (IC50)

HDAC3

1.70 μM (IC50)

体外研究
(In Vitro)

HDAC-IN-72 (0.1-50 μM, 48 h) 对乳腺癌细胞株 MCF-7 (IC50=0.83±1.41 μM) 和 T47D (IC50=1.4±1.85 μM) 有较好的抗增殖活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HDAC-IN-72 相关抗体:
分子量

359.42

Formula

C22H21N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HDAC-IN-72 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC-IN-72763066-77-9HDACHistone deacetylasesHistone deacetylase inhibitorsbenzamide-based derivativesHDAC inhibitorInhibitorinhibitorinhibit

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目录号：
HY-162487
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