2. Apoptosis
  3. TNF Receptor
  4. HDMAPP triammonium

HDMAPP triammonium 

目录号: HY-145498 纯度: ≥90.0%
COA 产品使用指南

摩尔计算器

HDMAPP triammonium 是一种铵盐形式的强效磷抗原，也是 (E)-HDMAPP 的焦磷酸盐形式。HDMAPP 还是 γδ T 细胞的有效激活因子，可在体外诱导 T 细胞的刺激反应 (EC50=0.39 nM, TNF-α)。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

HDMAPP triammonium Chemical Structure

HDMAPP triammonium Chemical Structure

CAS No. : 443892-56-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
500 μg ￥1598
In-stock

* Please select Quantity before adding items.

Customer Review

HDMAPP triammonium 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

查看所有亚型
TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HDMAPP triammonium is a potent phosphoantigen in the ammonium form and the pyrophosphate form of (E)-HDMAPP. HDMAPP is also a potent activator of γδ T cells and can induce T cell stimulation in vitro (EC50=0.39 nM, TNF-α)[1].

IC50 & Target[1]

TNFRSF1A

 

体外研究
(In Vitro)

HDMAPP triammonium (化合物 3E) (2 μM) 增加原代多克隆人 Vγ9Vδ2 T 细胞中的 TNF-α 释放水平，并具有刺激性生物活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HDMAPP triammonium 相关抗体:
体内研究
(In Vivo)

HDMAPP triammonium (化合物 3E) (0.02-2.5 mg/kg；静脉注射；15 天) 显着增加食蟹猴模型中的 γδ 细胞[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Nonhuman Primate Model in Cynomolgus[1]
Dosage: 0.02 mg/kg, 0.1 mg/kg, 0.5 mg/kg, 2.5 mg/kg
Administration: Intravenous injection; once with daily s.c. low doses IL-2 to sustain γδ-T-cell proliferation, for 15 days
Result: Significantly increased γδ-cells in vivo at 0.02 mg/kg. Reached maximal effect at 2.5 mg/kg.
分子量

313.18

Formula

C5H21N3O8P2
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥90.0%

COA (189 KB)

产品使用指南 (1538 KB)
参考文献

HDMAPP triammonium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDMAPP triammonium443892-56-6TNF ReceptorTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
HDMAPP triammonium
目录号：
HY-145498
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z