2. Epigenetics NF-κB
  3. Histone Demethylase NF-κB
  4. Helenalin acetate

Helenalin acetate 

目录号: HY-114519 纯度: 98.59%
COA 产品使用指南

摩尔计算器

Helenalin acetate 是一种天然的 NF-κB 抑制剂，也是一种有效的 C/EBPβ 抑制剂。 Helenalin acetate 具有抗炎和抗癌活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Helenalin acetate Chemical Structure

Helenalin acetate Chemical Structure

CAS No. : 10180-86-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥5500
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Helenalin acetate 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 Histone Demethylase 亚型特异性产品:

查看所有亚型
KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6 KDM7

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Helenalin acetate, a natural NF-κB inhibitor, is a potent C/EBPβ inhibitor. Helenalin acetate has anti-inflammatory and anticancer activities[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEp-2 ED50
0.29 μg/mL
Compound: 4
Cytotoxicity against human Hep2 cells assessed as growth inhibition by microtiter method
Cytotoxicity against human Hep2 cells assessed as growth inhibition by microtiter method
[PMID: 671468]
体外研究
(In Vitro)

Helenalin acetate（0.1-1 μM；持续 7 天）显着抑制 3T3-L1 细胞的分化[1]。
Helenalin acetate对急性髓性白血病细胞具有抗增殖作用，对正常造血祖细胞无作用[1]。
Helenalin acetate 通过结合到 C/EBPβ 的 N 末端部分来抑制 C/EBPβ，从而破坏 C/EBPβ 与共激活因子 p300 的合作。Helenalin acetate 仅选择性抑制全长（富含肝脏的激活蛋白* (LAP*)）同种型，但不抑制稍短的 (LAP) 同种型[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Helenalin acetate 相关抗体:

Cell Differentiation Assay[1]

Cell Line: 3T3-L1 cells
Concentration: 0.1 μM, 0.3 μM, 1 μM
Incubation Time: for 7 days
Result: Inhibited the differentiation significantly.
分子量

304.34

Formula

C17H20O5
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Helenalin acetate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Helenalin10180-86-6Histone DemethylaseNF-κBNuclear factor-κBNuclear factor-kappaBsesquiterpene lactoneC/EBPβanti-inflammatory and anticancer activitiesInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Helenalin acetate
目录号：
HY-114519
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z