2. Membrane Transporter/Ion Channel Apoptosis
  3. Na+/K+ ATPase Apoptosis
  4. Hellebrin

Hellebrin 是从植物中分离得到的一种 bufadienolide 类化合物，可抑制肿瘤细胞生长。Hellebrigenin 在克服癌细胞对凋亡刺激的抵抗方面有潜力，以及在多药耐药性 (MDR) 癌细胞模型中也显示出抗增殖效果。Hellebrin 可作用于 Na+/K+-ATPase 来调节细胞内的信号传导路径。

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Hellebrin Chemical Structure

Hellebrin Chemical Structure

CAS No. : 13289-18-4

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Hellebrin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hellebrin is a bufadienolide compound extracted from plants that can inhibit tumor cell growth. Hellebrigenin shows potential in overcoming cancer cells' resistance to apoptosis stimuli and has also demonstrated anti-proliferation effects in multidrug-resistant (MDR) cancer cell models. Hellebrin can act on Na+/K+-ATPase to regulate intracellular signaling pathways[1].

分子量

724.79

Formula

C36H52O15
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hellebrin 相关分类

  • 摩尔计算器

  • 稀释计算器

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hellebrin13289-18-4Na+/K+ ATPaseApoptosisSodium potassium pumpCardiotonic steroidsCardenolidesBufadienolidesCancerGlycoside / aglycone formsLactate release - oxygen consumptionInhibitorinhibitorinhibit

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