2. Anti-infection
  3. Bacterial
  4. Herbimycin C

Herbimycin C  (Synonyms: Antibiotic TAN 420D)

目录号: HY-126699
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摩尔计算器

Herbimycin C (Antibiotic TAN 420D) 是一种最初从 S. hygroscopicus 中分离出来的细菌代谢物。它对 HeLa 细胞和 Ehrlich 细胞具有细胞毒性（IC50s 分别为 7.3 和 1.2 μg/mL）。

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Herbimycin C Chemical Structure

Herbimycin C Chemical Structure

CAS No. : 91700-92-4

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Herbimycin C 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780 IC50
3.01 μM
Compound: 2
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
A-375 IC50
2.43 μM
Compound: 2
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
BGC-823 IC50
3.99 μM
Compound: 2
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
HCT-116 IC50
9.39 μM
Compound: 2
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
MCF7 IC50
5.07 μM
Compound: 2
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
SW1990 IC50
8.62 μM
Compound: 2
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
分子量

560.64

Formula

C29H40N2O9
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Herbimycin C 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Herbimycin C91700-92-4Antibiotic TAN 420DBacterialInhibitorinhibitorinhibit

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