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  4. hGAPDH-IN-1

hGAPDH-IN-1 是一种 3-bromo-4,5-dihydroisoxazole 衍生物，是一种特异且有效的 hGAPDH 共价抑制剂。hGAPDH-IN-1 抑制不同胰腺癌细胞系中的癌细胞增殖。

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hGAPDH-IN-1 Chemical Structure

hGAPDH-IN-1 Chemical Structure

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hGAPDH-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hGAPDH-IN-1, a 3-bromo-4,5-dihydroisoxazole derivative, is a specific and potent hGAPDH covalent inhibitor. hGAPDH-IN-1 reduces cancer cell growth in different pancreatic cancer cell lines.

体外研究
(In Vitro)

hGAPDH-IN-1 (化合物 11; 1-100 μM; 48 小时) 可显着降低腺癌细胞系中的癌细胞生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

hGAPDH-IN-1 相关抗体:

Cell Viability Assay[1]

Cell Line: PaCa-3, PaCa-44, PANC-1, and MIA PaCa-2 cell lines
Concentration: 1, 2.5, 5, 10, 25, 50, 100 μM
Incubation Time: 48 hours
Result: Turned out to strongly reduce cancer cell growth in all tested cell lines.
Had IC50s of 4.69 μM, 16.16 μM, 21.72 μM, 15.2 μM for PaCa-3, PaCa-44, PANC-1, and MIA PaCa-2 cell lines, respectively.
分子量

266.13

Formula

C12H12BrNO
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hGAPDH-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hGAPDH-IN-1Others3-bromo-4,5-dihydroisoxazolehGAPDHpancreatic cancerPaCa-3PaCa-44PANC-1MIA PaCa-2 cellInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-149076
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