2. Anti-infection
  3. Parasite
  4. HGPRT/TBrHGPRT1-IN-1

HGPRT/TBrHGPRT1-IN-1 (Compound 5) 是人类次黄嘌呤-鸟嘌呤磷酸核苷转移酶 HGPRT 和 布鲁氏锥虫 TBrHGPRT1 的选择性抑制剂 (Ki=3 nM)。 HGPRT/TBrHGPRT1-IN-1 通过抑制作用，最终导致细胞生长减少。HGPRT/TBrHGPRT1-IN-1 主要用于感染性疾病和癌症的研究。

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HGPRT/TBrHGPRT1-IN-1 Chemical Structure

HGPRT/TBrHGPRT1-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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HGPRT/TBrHGPRT1-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HGPRT/TBrHGPRT1-IN-1 (Compound 5) is a selective inhibitor targeting human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Trypanosoma bruce HGPRT1 (TBrHGPRT1) (both Ki=3 nM). HGPRT/TBrHGPRT1-IN-1 ultimately results in decreased cell growth. HGPRT/TBrHGPRT1-IN-1 is primarily used in the research of infectious diseases and cancer[1].

体外研究
(In Vitro)

HGPRT/TBrHGPRT1-IN-1 的抑制活力分别为 Ki=3 nM (human HGPRT); 10 nM (Pf HGXPRT); 60 nM (Pv HGPRT); 3 nM (TBr HGPRT1); 0.3 μM (Mtb HGPRT); 0.1 μM (Hp XGHPR); 4 μM (Ec XGPRT)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HGPRT/TBrHGPRT1-IN-1 相关抗体:
分子量

494.33

Formula

C15H24N6O9P2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HGPRT/TBrHGPRT1-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HGPRT/TBrHGPRT1-IN-1ParasiteCell growth inhibitionAntiparasitic Agentscancer;DNA/RNA synthesis inhibitorInhibitorinhibitorinhibit

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