2. 天然产物
  3. 植物 酚类
  4. 桦木科 多酚类
  5. 辽东桤木
  6. Hirsutanonol 5-O-β-D-glucopyranoside

Hirsutanonol 5-O-β-D-glucopyranoside  (Synonyms: Hirsutanonol 5-O-glucoside)

目录号: HY-N4043
产品使用指南

摩尔计算器

Hirsutanonol 5-O-glucoside 是一种从 Alnus hirsuta 中分离得到的二芳基庚类衍生物。Hirsutanonol 5-O-glucoside 对 HepG2 中 t-BHP 诱导的细胞毒性有显著的肝保护作用，保护率为 42.8%。

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Hirsutanonol 5-O-β-D-glucopyranoside Chemical Structure

Hirsutanonol 5-O-β-D-glucopyranoside Chemical Structure

CAS No. : 93915-36-7

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Hirsutanonol 5-O-β-D-glucopyranoside 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hirsutanonol 5-O-glucoside is a diarylheptanoid derivatives that can be isolated from Alnus hirsuta. Hirsutanonol 5-O-glucoside exhibits significant hepatoprotective effects against t-BHP-induced toxicity in HepG2 cells with 42.8% protection[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 IC50
10 μM
Compound: 4
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
[PMID: 33422907]
RAW264.7 IC50
29.4 μg/mL
Compound: 4
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay
[PMID: 33422907]
RAW264.7 IC50
33.7 μg/mL
Compound: 4
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis
[PMID: 33422907]
分子量

508.51

Formula

C25H32O11
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hirsutanonol 5-O-β-D-glucopyranoside 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hirsutanonol 5-O-β-D-glucopyranoside93915-36-7Hirsutanonol 5-O-glucosideOthersDiarylheptanoid derivativesHepG2Alnus hirsuteHepatoprotective effectsInhibitorinhibitorinhibit

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