2. Anti-infection
  3. Influenza Virus
  4. IAV-IN-2

IAV-IN-2 (Compound MC-22) 通过阻断甲型流感病毒 (IAV) 通过网格蛋白介导的内吞作用 (CME) 进入宿主细胞来抑制甲流。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

IAV-IN-2 Chemical Structure

IAV-IN-2 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

IAV-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IAV-IN-2 (Compound MC-22) inhibits for Influenza A Virus (IAV) through blocking the entry of IAV into host cell via clathrin-mediated endocytosis (CME)[1].

体外研究
(In Vitro)

IAV-IN-2 (0.01-10 µM) 抑制 IAV A/X-31 (H3N2) (IC50 为 4.08 µM)，A/WSN/33 (H1N1)，A/Udorn/72 (H3N2) 和 A/NYMC (H3N2)，抑制效力为 97%–100%[1]。
IAV-IN-2 (1-1000 μM) 在细胞 A549 中表现出细胞毒性，CC50 为 33.9 μM[1]。
IAV-IN-2 (10 μM) 会导致内体成熟缺陷，从而破坏病毒核心在内体运输过程中的逐步启动，使病毒无法脱去衣壳并释放基因组[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IAV-IN-2 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: A549
Concentration: 1-1000 μM
Incubation Time: 24 h
Result: Exhibited cytotoxicity in A549.
分子量

411.45

Formula

C22H25N3O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IAV-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IAV-IN-2Influenza VirusInfluenza AInhibitorinhibitorinhibit

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产品名称：
IAV-IN-2
目录号：
HY-158097
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