2. Immunology/Inflammation
  3. STING
  4. ISD sodium

ISD (interferon stimulatory DNA) sodium 是来自单核细胞增生李斯特菌基因组的 45 bp 双链非 CpG 寡聚物。当转染到细胞中时，ISD sodium 会强烈增强 IFN-β 的表达。这种 ISD 诱导的反应是由 STING-TBK1-IRF3 信号轴介导的。

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DNA, (5'-TACAGATCTACTAGTGATCTATGACTGATCTGTACATGATCTACA-3'), complex with DNA, (3'-ATGTCTAGATGATCACTAGATACTGACTAGACATGTACTAGATGT-5'), sodium salt

ISD sodium Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥2000
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5 mg ￥5000
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100 mg   询价  

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ISD sodium 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis[1].

性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

ISD sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ISDSTINGStimulator of Interferon GenesTMEM173MITAERISMPYSnon-CpG oligomerIFN-βSTING-TBK1-IRF3Inhibitorinhibitorinhibit

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产品名称：
ISD sodium
目录号：
HY-160225
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