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  4. Isonicotinaldehyde 2-pyridin

Isonicotinaldehyde 2-pyridin是一种具有抗利什曼原虫活性，能够有效对抗L. amazonensis和L. braziliensis的前鞭毛体。Isonicotinaldehyde 2-pyridin对小鼠巨噬细胞无显著毒性影响。Isonicotinaldehyde 2-pyridin的生物活性与增加活性氧物种（ROS）及干扰寄生虫线粒体功能密切相关。Isonicotinaldehyde 2-pyridin在药理作用机制的初步研究中显示了其对L. amazonensis的影响。

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Isonicotinaldehyde 2-pyridin Chemical Structure

Isonicotinaldehyde 2-pyridin Chemical Structure

CAS No. : 2241017-37-6

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Isonicotinaldehyde 2-pyridin 相关抗体

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  • 生物活性

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生物活性

Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action[1].

分子量

198.22

Formula

C11H10N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Isonicotinaldehyde 2-pyridin 相关分类

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Keywords:

Isonicotinaldehyde 2-pyridin2241017-37-6OthersInhibitorinhibitorinhibit

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