2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Itameline

Itameline  (Synonyms: 伊他美林; RU 47213)

目录号: HY-U00085
产品使用指南

摩尔计算器

Itameline (RU 47213) 是一种具有口服活性和长效胆碱能活性的前体化合物。Itameline 是一种新型四氢吡啶肟，可在体内裂解形成活性代谢物 RU 35963，这是一种对受体亚型无选择性的毒蕈碱受体激动剂。Itameline 具有减轻大鼠胆碱能传递障碍引起的记忆缺陷的能力。

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Itameline Chemical Structure

Itameline Chemical Structure

CAS No. : 145071-44-9

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Itameline 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Itameline (RU 47213) is a prodrug with oral and long-lasting cholinergic activity. Itameline is a novel tetrahydropyridine-oxime that is cleaved in vivo to form an active metabolite, RU 35963. RU 35963 is a muscarinic receptor agonist that is nonselective with respect to receptor subtypes. Itameline possesses the capacity to reduce memory deficits induced by an impairment of cholinergic transmission in the rat[1].

分子量

294.73

Formula

C14H15ClN2O3
CAS 号
中文名称

伊他美林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Itameline 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Itameline145071-44-9RU 47213伊他美林RU47213RU-47213Cholinesterase (ChE)Prodrugoralcholinergictetrahydropyridine-oximeRU 35963memory deficitcholinergic transmissionInhibitorinhibitorinhibit

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