2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. JYQ-173

JYQ-173 人类帕金森病蛋白 7 (PARK7) 的选择性抑制剂，IC50 为 19 nM。JYQ-173 具有良好的细胞通透性。JYQ-173 是靶蛋白 PARK7 的配体，可用于合成 PROTAC Degrader JYQ-194 (HY-163564)。

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JYQ-173 Chemical Structure

JYQ-173 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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JYQ-173 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JYQ-173 is a selective inhibitor for human Parkinson disease protein 7 (PARK7), with an IC50 of 19 nM. JYQ-173 exhibits good cell permeability. JYQ-173 is the ligand for target protein PARK7, which can be utilized for synthesis of PROTAC Degrader JYQ-194 (HY-163564)[1].

IC50 & Target

IC50: 19 nM (PARK7)
分子量

466.49

Formula

C21H19FN8O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

JYQ-173 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JYQ-173JYQ173JYQ 173Ligands for Target Protein for PROTACTarget Protein-binding MoietyUbiquitinationDegradationCancerNeurodegenerative DiseasesParkinson's diseaseA549Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-163563
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