2. NF-κB
  3. Keap1-Nrf2
  4. Keap1-Nrf2-IN-15

Keap1-Nrf2-IN-15 (Compound 24a) 是一种有效的 Keap1-Nrf2 蛋白-蛋白相互作用抑制剂，其在 FP 试验和 TR-FRET 试验中的 IC50 分别为 77 nM 和 2.5 nM。

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Keap1-Nrf2-IN-15 Chemical Structure

Keap1-Nrf2-IN-15 Chemical Structure

CAS No. : 2456295-45-5

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Keap1-Nrf2-IN-15 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Keap1-Nrf2-IN-15 (Compound 24a) is a potent Keap1-Nrf2 protein-protein interaction inhibitor with IC50s of 77 nM and 2.5 nM in FP assay and TR-FRET assay, respectively[1].

体外研究
(In Vitro)

Keap1-Nrf2-IN-15 (Compound 24a) 与 Keap1 蛋白结合[1]。
Keap1-Nrf2-IN-15 (10 and 100 μM; 24 h) 导致 Nrf2 靶基因 (HMOX1、GSTM3、NQO1) 在 NCM460D 细胞中显著诱导[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Keap1-Nrf2-IN-15 相关抗体:
分子量

801.84

Formula

C39H35N3O12S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Keap1-Nrf2-IN-15 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Keap1-Nrf2-IN-152456295-45-5Keap1-Nrf2HMOX1GSTM3NQO1NCM460DInhibitorinhibitorinhibit

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