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  4. Kobusine derivative-2

Kobusine derivative-2 是一种 kobusine 衍生物，对癌细胞具有抗增殖活性。Kobusine derivative-2 可诱导 MDA-MB-231 细胞阻滞在亚 G1 期。具有抗癌活性。

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Kobusine derivative-2 Chemical Structure

Kobusine derivative-2 Chemical Structure

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Kobusine derivative-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity[1].

体外研究
(In Vitro)

Kobusine derivative-2 (compound 25) (0-20 μM; 72 h) has antiproliferative activity against cancer cell lines A549, MDA-MB-231, MCF-7, KB and KB-VIN[1].
Kobusine derivative-2 (12 or 24 h; 13.3 μM) arrests MDA-MB-231 cells at the sub-G1 phase[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Kobusine derivative-2 相关抗体:

Cell Proliferation Assay[1]

Cell Line: A549, MDA-MB-231, MCF-7, KB and KB-VIN
Concentration: 0-20 μM
Incubation Time: 72 h
Result: Exhibited antiproliferative activity against cancer cell lines A549, MDA-MB-231, MCF-7, KB and KB-VIN with IC50s of 4.4 μM, 4.2 μM, 4.5 μM, 4.5 μM and 4.6 μM, respectively.

Cell Cycle Analysis[1]

Cell Line: MDA-MB-231
Concentration: 12 or 24 h
Incubation Time: 13.3 μM (3-fold of IC50)
Result: Decreased numbers of cells in S and G2/M phases, resulting in accumulation of sub-G1.
分子量

687.48

Formula

C36H35Cl4NO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kobusine derivative-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kobusine derivative-2Kobusine derivative2Kobusine derivative 2OthersanticancerA549MDA-MB-231MCF-7KBKB-VINInhibitorinhibitorinhibit

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产品名称：
Kobusine derivative-2
目录号：
HY-149033
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