2. Apoptosis
  3. Apoptosis
  4. Koenimbine

Koenimbine 是一种抗癌剂，可从 Murraya koenigii 的叶子和果实中获得。Koenimbine 能诱导 HT-29 和 SW48 细胞凋亡 (apoptosis) 和坏死，具有研究癌症的潜力。

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Koenimbine Chemical Structure

Koenimbine Chemical Structure

CAS No. : 21087-98-9

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Koenimbine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16-4A5 IC50
1.2 μM
Compound: 13
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
[PMID: 23376010]
DU-145 IC50
0.2 μM
Compound: 35
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
HCT-116 IC50
0.2 μM
Compound: 35
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
HeLa IC50
0.2 μM
Compound: 35
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
HepG2 IC50
0.2 μM
Compound: 35
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
OVCAR-3 IC50
0.2 μM
Compound: 35
Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
PA-1 IC50
0.2 μM
Compound: 35
Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 34838335]
分子量

293.36

Formula

C19H19NO2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Koenimbine 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Koenimbine21087-98-9ApoptosisHT-29SW48cancerapoptosisMurraya koenigiinecrosisInhibitorinhibitorinhibit

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