2. PI3K/Akt/mTOR
  3. PI4K
  4. KR-27370

KR-27370 (compound 7f) 是一种抗病毒剂和选择性的 PI4KIIIβ/PI4KIIIα 抑制剂 (IC50: 3.1 nM/15.8 nM)，对 hRV、柯萨奇病毒和其他肠道病毒具有抑制活性[1].br/

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KR-27370 Chemical Structure

KR-27370 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

KR-27370 相关抗体

Top Publications Citing Use of Products

查看 PI4K 亚型特异性产品:

查看所有亚型
PI4KIIIβ PI4KIIIα PI4K PI4KII

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KR-27370 (compound 7f) is an antiviral agent and selective PI4KIIIβ/PI4KIIIα inhibitor (IC50: 3.1 nM/15.8 nM), against hRV, Ke Saatchivirus and other enteroviruses have inhibitory activity[1].br/[1].

IC50 & Target

PI4KIIIβ

3.1 nM (IC50, [1])

PI4KIIIα

15.8 nM (IC50, [1])

体外研究
(In Vitro)

KR-27370 的细胞毒性低 (CC50: >100 μM, H1HeLa)，对 hRV B14，hRV A16，hRV A21 的 EC50 分别为 22 nM，32 nM，36 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

KR-27370 相关抗体:
分子量

553.65

Formula

C27H27N3O6S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KR-27370 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KR-27370KR27370KR 27370PI4KPhosphatidylinositol 4 kinasesPI4 kinaseshRVcoxsackievirusenterovirusInhibitorinhibitorinhibit

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产品名称：
KR-27370
目录号：
HY-161357
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