2. 多肽产品
  3. 多肽及其衍生物
  4. 抑制剂与底物肽
  5. KSL 128114

KSL 128114是一种 syntenin 肽抑制剂，与syntenin的PDZ1结构域结合，亲和力达到纳摩尔级。KSL 128114在人血浆和鼠肝微粒体中不易被降解，并且对syntenin具有PDZ结构域选择性。

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Custom Peptide Synthesis

KSL 128114 Chemical Structure

KSL 128114 Chemical Structure

CAS No. : 2757292-12-7

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Customer Review

KSL 128114 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin[1].

体外研究
(In Vitro)

KSL-128114 (~20 μM) 对原发性GBM细胞活力具有抑制作用，并在患者来源的异种移植小鼠模型中显著延长了生存时间。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

KSL 128114 相关抗体:
分子量

2201.59

Formula

C96H165N39O21
CAS 号
Sequence

Ac-{d-Arg}-Arg-{d-Arg}-Gly-{d-Arg}-Lys-{d-Lys}-Arg-{d-Arg}-Ser-His-Trp-Tle-Chg-Asp-Ile
Sequence Shortening

Ac-{d-Arg}-R-{d-Arg}-G-{d-Arg}-K-{d-Lys}-R-{d-Arg}-SHW-{Tle-Chg}-DI
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KSL 128114 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KSL 1281142757292-12-7KSL128114KSL-128114OthersGBMsynteninPDZ1Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P10331
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