1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. KT-362 free acid

KT-362 free acid 是一种细胞内钙拮抗剂,具有抗心律失常和血管舒张效应。KT-362 free acid 显示出对去甲肾上腺素 (NE) 诱导的血管收缩反应的拮抗作用,通过减少肌醇磷脂水解来实现,从而降低细胞内钙的动员。KT-362 free acid 可用于研究血管平滑肌的收缩和舒张机制,特别是在探索细胞内钙动员和肌醇磷脂水解在血管收缩中的作用。

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KT-362 free acid Chemical Structure

KT-362 free acid Chemical Structure

CAS No. : 93392-97-3

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  • 生物活性

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  • 参考文献

生物活性

KT-362 free acid is an intracellular calcium antagonist with antiarrhythmic and vasodilatory effects. KT-362 free acid shows an antagonistic effect against norepinephrine (NE) induced vasoconstriction response, achieved by reducing inositol phospholipid hydrolysis, thereby reducing intracellular calcium mobilization. KT-362 free acid can be used to study the contraction and relaxation mechanisms of vascular smooth muscle, especially in exploring the role of intracellular calcium mobilization and inositol phospholipid hydrolysis in vascular contraction[1].

分子量

400.53

Formula

C22H28N2O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KT-362 free acid
目录号:
HY-101607A
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