2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. L-703606

L-703606 是一种有效的，选择性 NK1 受体拮抗剂。L-703606 可用于胃酸分泌的研究。

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L-703606 Chemical Structure

L-703606 Chemical Structure

CAS No. : 144425-84-3

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规格 是否有货
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L-703606 的其他形式现货产品:

Other Forms of L-703606:

L-703606 相关抗体

Top Publications Citing Use of Products

查看 Neurokinin Receptor 亚型特异性产品:

查看所有亚型
NK1 NK2 NK3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-703606 is a potent, selective antagonist of NK1 receptor. L-703606 can be used for study of gastric acid secretion[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
TAMH IC50
17.2 μM
Compound: 4; L-703,606
Cytotoxicity against TAMH assessed as reduction in cell viability by CellTiter-Glo assay
Cytotoxicity against TAMH assessed as reduction in cell viability by CellTiter-Glo assay
[PMID: 27173385]
TAMH IC50
64.28 μM
Compound: 4; L-703,606
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 10 uM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 10 uM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
[PMID: 27173385]
TAMH IC50
78.19 μM
Compound: 4; L-703,606
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 1 uM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 1 uM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
[PMID: 27173385]
TAMH IC50
80.9 μM
Compound: 4; L-703,606
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 100 nM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
Cytotoxicity against TAMH assessed as chloroquine IC50 by measuring reduction in cell viability at 100 nM by CellTiter-Glo assay (Rvb = 85.26 +/- 3.01 uM)
[PMID: 27173385]
分子量

508.44

Formula

C27H29IN2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-703606 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-703606144425-84-3L703606L 703606Neurokinin ReceptorNK receptorTachykinin receptorgastric acid secretionInhibitorinhibitorinhibit

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目录号：
HY-117216
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